Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997735 | 1.00 | MAPT (0.62) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL997194 | 0.95 | MAPT (0.62) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL997192 | 0.95 | MAPT (0.62) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL998256 | 0.88 | ABCG2 (0.67) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL998254 | 0.88 | ABCG2 (0.67) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL996603 | 0.87 | AR (0.50) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL996606 | 0.87 | AR (0.50) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL996200 | 0.86 | PDE4A (0.64) | MAPTKMT2AMEN1ABCG2TNFRSF1A | |
| SCHEMBL996198 | 0.86 | PDE4A (0.64) | MAPTKMT2AMEN1ABCG2TNFRSF1A | |
| SCHEMBL997653 | 0.85 | MAPT (0.54) | MAPTKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | claimed |
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |