Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 13/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9982962 | 0.83 | MAPK1 (0.36) | ELANEFPR2SCN9A | |
| SCHEMBL2211147 | 0.79 | ELANE (0.43) | PPARDELANE | |
| SCHEMBL2211151 | 0.79 | ELANE (0.43) | PPARDELANE | |
| SCHEMBL9983344 | 0.77 | CMA1 (0.39) | PPARDELANECMA1 | |
| SCHEMBL14174347 | 0.77 | ELANE (0.42) | ELANE | |
| SCHEMBL9983132 | 0.75 | ALDH1A1 (0.46) | ELANECMA1 | |
| SCHEMBL2209205 | 0.70 | XIAP (0.38) | — | |
| SCHEMBL2209197 | 0.70 | XIAP (0.38) | — | |
| SCHEMBL9983017 | 0.65 | GPBAR1 (0.34) | FPR2SCN9A | |
| SCHEMBL2209206 | 0.58 | ELANE (0.47) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319614-A1 | Organic Compounds | NOVARTIS AG (CH) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319614-A1 | Organic Compounds | XIAP, BIRC5, BIRC3 | PPARD 4530/4885ELANE 592/4885FPR2 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.