Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | PGC | P20142 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547685 | 0.95 | UGT1A1 (0.48) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3548530 | 0.94 | UGT1A1 (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3553633 | 0.94 | UGT1A1 (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3548529 | 0.94 | UGT1A1 (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3554383 | 0.93 | UGT1A1 (0.57) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3551192 | 0.93 | UGT1A1 (0.54) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3554319 | 0.92 | CTSD (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3554314 | 0.92 | CTSD (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3554317 | 0.92 | CTSD (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR | |
| SCHEMBL3549159 | 0.92 | CTSD (0.47) | UGT1A1ABCB11ABCB1ABCG2MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697348-B1 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LAB (US) | 2011-12-28 | — | — | EP | claimed |