Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105949 | 0.75 | GYS1 (0.46) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL16142446 | 0.75 | MAOB (0.43) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL2433939 | 0.73 | GYS1 (0.46) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL16106003 | 0.73 | KMT2A (0.43) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL14796812 | 0.73 | KMT2A (0.37) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL14796827 | 0.73 | KMT2A (0.38) | MAOBGYS1KMT2AKDM5AKDM4C | |
| Bicarbonate SCHEMBL14796760 | 0.72 | GYS1 (0.47) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL2431388 | 0.72 | KDM5A (0.47) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL16106041 | 0.72 | GYS1 (0.45) | MAOBGYS1KMT2AKDM5AKDM4C | |
| SCHEMBL2432449 | 0.72 | FFAR4 (0.53) | GYS1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582674-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | Metabolex Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159297-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |