Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752851 | 0.80 | HSD17B10 (0.37) | HPGDNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7213741 | 0.75 | HPGD (0.40) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL27754207 | 0.75 | HPGD (0.36) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL28205931 | 0.74 | TYR (0.38) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL27754223 | 0.74 | ALDH1A1 (0.41) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL27754218 | 0.71 | ALDH1A1 (0.40) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL4954240 | 0.70 | BCL6 (0.40) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL6277959 | 0.70 | HPGD (0.43) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL30319942 | 0.69 | BCL6 (0.39) | HPGDNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9983754 | 0.69 | CNR1 (0.37) | HPGDSMN1; SMN2NPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157339-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-12-22 | — | — | WO | disclosed |