Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 6/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129656 | 1.00 | HTR1A (0.39) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL9983886 | 1.00 | HTR1A (0.39) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL2130552 | 1.00 | HTR1A (0.39) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL9985624 | 0.88 | SSTR1 (0.40) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL9985621 | 0.88 | SSTR1 (0.40) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL14841706 | 0.88 | SSTR1 (0.40) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL15610890 | 0.87 | PTPN1 (0.43) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL2131297 | 0.87 | PTPN1 (0.43) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL20643059 | 0.87 | PTPN1 (0.43) | HTR1APTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL9986263 | 0.87 | PTPN1 (0.43) | HTR1APTPN1CDC25BPTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159067-A2 | THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN CROSS CORPORATION (KR) | 2011-12-22 | — | — | WO | disclosed |