Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6315264 | 1.00 | — | — | |
| Acetic Acid SCHEMBL7456705 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL23548939 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL9053450 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL3645655 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL2907405 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL3451040 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL9599616 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL2677437 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL7118694 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098203-A1 | LUBRICANT COMPOSITION FOR RESIN CONVEYOR AND METHOD FOR USING SAME | DIVERSEY, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-7875581-B2 | excels in washing ability, lubricating ability and prevents stress cracking of polyalkylene terephthalate containers; storage stability | DIVERSEY, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| EP-2144984-A2 | LUBRICANT COMPOSITION FOR RESIN CONVEYOR AND METHOD FOR USING SAME | JohnsonDiversey, Inc., (US) | 2010-01-20 | — | — | EP | disclosed |
| US-20090029886-A1 | LUBRICANT COMPOSITION FOR RESIN CONVEYOR AND METHOD FOR USING SAME | JOHNSONDIVERSEY, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| WO-2007051011-A2 | LUBRICANT COMPOSITION FOR RESIN CONVEYOR AND METHOD FOR USING SAME | JOHNSONDIVERSEY, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2001031109-A9 | SHOE BAGS FOR USE IN LAUNDERING PROCESSES | PROCTER & GAMBLE (US) | 2002-05-10 | — | — | WO | disclosed |
| US-4694050-A | Process for absorbing polar materials using transamidated poly-2-oxazoline compositions | THE DOW CHEMICAL COMPANY (US) | 1987-09-15 | — | — | US | disclosed |