Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL23548939 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL6315264 | 0.96 | — | — | |
| Acetic Acid SCHEMBL7456705 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL998512 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL3645655 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Piperazine SCHEMBL7327328 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL3451040 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL9599616 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL2677437 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 | |
| Acetic Acid SCHEMBL2907405 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8271508-A | — | — | None | — | — | JP | disclosed |
| JP-H08271508-A | BLOOD INSPECTION CASE AND CARRIER | SEKISUI CHEM CO LTD | 1996-10-18 | — | — | JP | disclosed |