Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985780 | 0.92 | TNNI3K (0.43) | TNNI3KBRAF | |
| SCHEMBL9986569 | 0.90 | TNNI3K (0.45) | TNNI3KBRAF | |
| SCHEMBL9985735 | 0.87 | TNNI3K (0.46) | TNNI3KBRAF | |
| SCHEMBL9985716 | 0.83 | TNNI3K (0.56) | TNNI3KBRAF | |
| SCHEMBL9985447 | 0.82 | CDK2 (0.47) | TNNI3K | |
| SCHEMBL9986144 | 0.82 | TNNI3K (0.41) | TNNI3KBRAF | |
| SCHEMBL9985477 | 0.81 | TNNI3K (0.63) | TNNI3KBRAF | |
| SCHEMBL9986382 | 0.79 | TNNI3K (0.42) | TNNI3KBRAF | |
| SCHEMBL9985668 | 0.78 | TNNI3K (0.44) | TNNI3KBRAF | |
| SCHEMBL9986248 | 0.78 | TNNI3K (0.60) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |