Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | C1R | P00736 | 10/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ELANE | P08246 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | CTSG | P08311 | 2/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK14 | Q9P0G3 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914556 | 0.89 | C1R (0.72) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL9984778 | 0.86 | APEX1 (0.76) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL915740 | 0.84 | APEX1 (1.00) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL4194349 | 0.84 | APEX1 (0.72) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL5299192 | 0.83 | C1R (1.00) | C1RKMT2AELANEMAPTALDH1A1 | |
| SCHEMBL916155 | 0.82 | APEX1 (0.69) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL9984612 | 0.81 | ELANE (1.00) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL913800 | 0.80 | APEX1 (0.67) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL14571464 | 0.79 | APEX1 (0.65) | APEX1C1RKMT2AELANEMAPT | |
| SCHEMBL6567250 | 0.78 | APEX1 (0.63) | APEX1C1RKMT2AELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319611-A1 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CHANG GUNG UNIVERSITY (TW) | 2011-12-29 | — | — | US | claimed |
| US-20110319611-A1 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CHANG GUNG UNIVERSITY (TW) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319611-A1 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CYP4X1, CYP2B6, CYP2C19 | APEX1 3474/4885C1R 84/4885KMT2A 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.