Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986286 | 1.00 | DPP4 (0.45) | DPP4CYP3A4DPP7PIN1DPP8 | |
| SCHEMBL13084119 | 0.88 | DPP4 (0.45) | DPP4CYP3A4DPP7DPP8DPP9 | |
| SCHEMBL15108790 | 0.85 | DPP4 (0.40) | DPP4CYP3A4 | |
| SCHEMBL3705644 | 0.84 | DPP4 (0.44) | DPP4CYP3A4PIN1 | |
| SCHEMBL743044 | 0.83 | DPP4 (0.42) | DPP4CYP3A4DPP7PIN1DPP8 | |
| SCHEMBL16750215 | 0.83 | DPP4 (0.42) | DPP4CYP3A4DPP7PIN1DPP8 | |
| SCHEMBL744346 | 0.83 | DPP4 (0.42) | DPP4CYP3A4DPP7PIN1DPP8 | |
| SCHEMBL7932108 | 0.81 | DPP4 (0.40) | DPP4CYP3A4DPP7PIN1DPP8 | |
| SCHEMBL4751469 | 0.81 | DPP4 (0.38) | DPP4CYP3A4DPP7DPP8DPP9 | |
| SCHEMBL15108785 | 0.81 | PIN1 (0.41) | DPP4CYP3A4DPP7PIN1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397141-A1 | Process for the synthesis of beta-amino acids and derivatives thereof | LEK Pharmaceuticals d.d. (SI) | 2011-12-21 | — | — | EP | disclosed |
| EP-2397141-A1 | Process for the synthesis of beta-amino acids and derivatives thereof | LEK Pharmaceuticals d.d. (SI) | 2011-12-21 | — | — | EP | disclosed |