Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985770 | 0.90 | FFAR4 (0.46) | GYS1KDM5AKDM4CPPARAFFAR4 | |
| SCHEMBL2462337 | 0.87 | PPARD (0.52) | PPARAPPARGPPARD | |
| SCHEMBL2462339 | 0.87 | PPARD (0.52) | PPARAPPARGPPARD | |
| SCHEMBL2999641 | 0.87 | PPARD (0.52) | PPARAPPARGPPARD | |
| SCHEMBL2431887 | 0.84 | FFAR1 (0.51) | GYS1PPARAPPARGPPARD | |
| SCHEMBL2467739 | 0.82 | GYS1 (0.44) | GYS1SCN3AKDM5AKDM4CKMT2A | |
| Bicarbonate SCHEMBL14796760 | 0.79 | GYS1 (0.47) | GYS1KDM5AKDM4CKMT2AMAOB | |
| SCHEMBL2431602 | 0.78 | GYS1 (0.41) | GYS1KDM5AKDM4CKMT2AMAOB | |
| Bicarbonate SCHEMBL14796865 | 0.78 | GYS1 (0.47) | GYS1KDM5AKDM4CKMT2AMAOB | |
| SCHEMBL2431388 | 0.77 | KDM5A (0.47) | GYS1KDM5AKDM4CKMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582674-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | Metabolex Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159297-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |