Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985176 | 0.85 | CYP17A1 (0.43) | BRD4KMT2AMEN1CYP17A1CYP19A1 | |
| SCHEMBL9984879 | 0.83 | BRD4 (0.45) | BRD4KMT2AMEN1L3MBTL1CYP19A1 | |
| SCHEMBL9984119 | 0.82 | BRD4 (0.44) | BRD4KMT2AMEN1CYP19A1HSF1 | |
| SCHEMBL9984994 | 0.81 | BRD4 (0.43) | BRD4KMT2AMEN1CYP17A1CYP19A1 | |
| SCHEMBL9984735 | 0.80 | BRD4 (0.45) | BRD4KMT2AMEN1L3MBTL1HSF1 | |
| SCHEMBL9985113 | 0.80 | EGFR (0.43) | BRD4CYP19A1HSF1MAPT | |
| SCHEMBL9985029 | 0.80 | BRD4 (0.42) | BRD4KMT2AMEN1CYP17A1CYP19A1 | |
| SCHEMBL9983283 | 0.80 | GAA (0.43) | BRD4KMT2AMEN1L3MBTL1CYP19A1 | |
| SCHEMBL9984024 | 0.79 | BRD4 (0.41) | BRD4CYP19A1HSF1MAPT | |
| SCHEMBL9984037 | 0.78 | BRD4 (0.41) | BRD4KMT2ACYP17A1L3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |