SCHEMBL9984994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9984879	0.92	BRD4 (0.45)	BRD4HSF1CYP26A1MAPTALDH1A1
	SCHEMBL9984119	0.91	BRD4 (0.44)	BRD4HSF1CYP26A1MAPTMAPK1
	SCHEMBL9985113	0.89	EGFR (0.43)	BRD4HSF1CYP26A1MAPTMAPK1
	SCHEMBL9985029	0.89	BRD4 (0.42)	BRD4CYP17A1HSF1CYP26A1MAPT
	SCHEMBL9985176	0.89	CYP17A1 (0.43)	BRD4CYP17A1HSF1CYP26A1MAPT
	SCHEMBL9983283	0.89	GAA (0.43)	BRD4CYP26A1MAPTGAAALDH1A1
	SCHEMBL9984024	0.88	BRD4 (0.41)	BRD4HSF1CYP26A1MAPTMAPK1
	SCHEMBL9984037	0.87	BRD4 (0.41)	BRD4CYP17A1HSF1CYP26A1MAPT
	SCHEMBL9984735	0.85	BRD4 (0.45)	BRD4HSF1CYP26A1MAPTRAB9A
	SCHEMBL9984881	0.85	CYP17A1 (0.48)	BRD4CYP17A1POLBMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.