Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730888 | 0.80 | MEN1 (0.35) | TSHRTDP1KMT2A | |
| SCHEMBL11500636 | 0.80 | PTPN1 (0.43) | TSHRMAPTPLA2G2C | |
| SCHEMBL2794842 | 0.79 | TSHR (0.39) | TSHRKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6545145 | 0.78 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL10809091 | 0.77 | CYP2D6 (0.43) | TSHRKMT2AALDH1A1MAPT | |
| SCHEMBL17258300 | 0.76 | HSD17B10 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL11671624 | 0.76 | TSHR (0.37) | TSHRTDP1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28469184 | 0.76 | TDP1 (0.33) | TDP1 | |
| SCHEMBL27607756 | 0.76 | SPHK1 (0.33) | TSHRTDP1ALDH1A1 | |
| SCHEMBL29106764 | 0.75 | TSHR (0.38) | TSHRALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252639-B1 | FOAMED MATERIALS COMPRISING A MATRIX HAVING A HIGH HARDBLOCK CONTENT AND PROCESS FOR PREPARING THEM | HUNTSMAN INT LLC (US) | 2013-05-15 | — | — | EP | disclosed |
| US-8349908-B2 | Foamed materials comprising a matrix having a high highblock content and process for preparing them | HUNTSMAN INTERNATIONAL LLC (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110015287-A1 | FOAMED MATERIALS COMPRISING A MATRIX HAVING A HIGH HIGHBLOCK CONTENT AND PROCESS FOR PREPARING THEM | HUNTSMAN INTERNATIONAL LLC (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2252639-A1 | FOAMED MATERIALS COMPRISING A MATRIX HAVING A HIGH HARDBLOCK CONTENT AND PROCESS FOR PREPARING THEM | Huntsman International LLC (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009109600-A1 | FOAMED MATERIALS COMPRISING A MATRIX HAVING A HIGH HARDBLOCK CONTENT AND PROCESS FOR PREPARING THEM | HUNTSMAN INTERNATIONAL LLC (US) | 2009-09-11 | — | — | WO | disclosed |