Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIK1 | P57059 | 2/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984937 | 0.92 | MAPT (0.42) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9984454 | 0.91 | ACVR1 (0.42) | CSF1RCDK6ALDH1A1MAPTMAPK1 | |
| SCHEMBL9988236 | 0.90 | BCL2L2 (0.36) | BCL2L2CSF1RCDK6ALDH1A1MAPT | |
| SCHEMBL9984717 | 0.89 | PLK1 (0.38) | CSF1RCDK6ALDH1A1MAPTMAPK1 | |
| SCHEMBL9983902 | 0.89 | SYK (0.37) | CSF1RCDK6ALDH1A1MAPTMAPK1 | |
| SCHEMBL9987422 | 0.87 | TDP1 (0.40) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9985355 | 0.83 | MAPT (0.41) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9985628 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9983856 | 0.82 | MAPT (0.39) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9984365 | 0.80 | MAPT (0.40) | CSF1RCDK6ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |