Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987418 | 0.98 | GCK (1.00) | GCKGRM5 | |
| SCHEMBL9987134 | 0.96 | GCK (0.93) | GCK | |
| SCHEMBL9986891 | 0.89 | GCK (1.00) | GCKGRM5 | |
| SCHEMBL9987189 | 0.85 | GCK (0.72) | GCKGRM5 | |
| SCHEMBL12070398 | 0.84 | GCK (0.72) | GCK | |
| SCHEMBL9987615 | 0.83 | GCK (0.73) | GCKGRM5 | |
| SCHEMBL9988005 | 0.83 | GCK (1.00) | GCK | |
| SCHEMBL9987471 | 0.81 | GCK (0.74) | GCK | |
| SCHEMBL9987175 | 0.80 | GCK (1.00) | GCK | |
| SCHEMBL9988014 | 0.80 | GCK (0.86) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | claimed |
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011158149-A1 | 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES | PFIZER INC. (US) | 2011-12-22 | — | — | WO | disclosed |