Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.66 |
| ▸ | PGR | P06401 | 10/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987160 | 0.89 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL292666 | 0.81 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL290565 | 0.78 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292130 | 0.77 | NR3C1 (0.87) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5647236 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL293330 | 0.77 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL291473 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL300099 | 0.76 | NR3C1 (0.87) | NR3C1NR3C2PGR | |
| SCHEMBL9987961 | 0.75 | NR3C1 (0.65) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL9988274 | 0.74 | NR3C1 (0.78) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |