Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 17/20 | 0.44 |
| ▸ | PGR | P06401 | 14/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291508 | 0.80 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL291288 | 0.70 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL5820785 | 0.68 | NR3C1 (0.52) | NR3C1NR3C2PGRSLC6A4SLC6A2 | |
| SCHEMBL4573135 | 0.66 | KCNH2 (0.38) | NR3C1NR3C2PGRSLC6A4SLC6A2 | |
| SCHEMBL24873061 | 0.64 | KCNH2 (0.52) | SLC6A4SLC6A2KCNH2 | |
| SCHEMBL293688 | 0.61 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL4162149 | 0.61 | NR3C1 (0.76) | NR3C1NR3C2PGR | |
| SCHEMBL29991828 | 0.61 | HTR2C (0.47) | NR3C1NR3C2PGRPIN1 | |
| SCHEMBL293015 | 0.61 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL292635 | 0.60 | NR3C1 (0.76) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |