Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291678 | 0.92 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL292081 | 0.88 | NR3C1 (0.79) | NR3C1NR3C2PGR | |
| SCHEMBL9987225 | 0.85 | NR3C1 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL292881 | 0.83 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL5524955 | 0.82 | NR3C1 (0.83) | NR3C1NR3C2PGR | |
| SCHEMBL5520858 | 0.81 | NR3C1 (0.84) | NR3C1NR3C2PGR | |
| SCHEMBL5527820 | 0.80 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL5523559 | 0.80 | NR3C1 (0.81) | NR3C1NR3C2PGR | |
| SCHEMBL5524358 | 0.80 | NR3C1 (0.87) | NR3C1NR3C2PGR | |
| SCHEMBL5522506 | 0.80 | NR3C1 (0.70) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |