Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.68 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.68 |
| ▸ | PGR | P06401 | 14/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291349 | 0.95 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291868 | 0.95 | NR3C1 (0.75) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5798341 | 0.87 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL15756276 | 0.87 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6382795 | 0.87 | NR3C1 (0.77) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL15756275 | 0.86 | NR3C1 (0.75) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6383343 | 0.86 | NR3C1 (0.76) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291968 | 0.85 | NR3C1 (0.75) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1932435 | 0.85 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1932878 | 0.85 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |