Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.53 |
| ▸ | PGR | P06401 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293938 | 0.83 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL5517667 | 0.81 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL5525001 | 0.81 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL4942167 | 0.81 | NR3C1 (0.66) | NR3C1NR3C2PGR | |
| SCHEMBL1634238 | 0.80 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL5515884 | 0.80 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL5521694 | 0.77 | NR3C1 (0.72) | NR3C1NR3C2PGR | |
| SCHEMBL5516501 | 0.77 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL292447 | 0.77 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL4825500 | 0.76 | NR3C1 (0.65) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |