Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | ROS1 | P08922 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984893 | 0.96 | ALDH1A1 (0.45) | ALDH1A1SYKMAPTMAPK1POLB | |
| SCHEMBL9984527 | 0.95 | MAPT (0.43) | ALDH1A1SYKRETROS1FLT3 | |
| SCHEMBL9984347 | 0.95 | MAPT (0.43) | ALDH1A1SYKRETROS1FLT3 | |
| SCHEMBL9983771 | 0.94 | FLT3 (0.46) | ALDH1A1RETROS1FLT3EML4 | |
| SCHEMBL9984333 | 0.94 | SYK (0.46) | ALDH1A1SYKRETROS1FLT3 | |
| SCHEMBL9984604 | 0.94 | SYK (0.36) | ALDH1A1SYKRETROS1FLT3 | |
| SCHEMBL9985177 | 0.94 | MAPT (0.42) | ALDH1A1MAPTMAPK1LMNAGAA | |
| SCHEMBL9984480 | 0.93 | MAPT (0.49) | ALDH1A1SYKRETROS1FLT3 | |
| SCHEMBL9984999 | 0.92 | MAPT (0.39) | ALDH1A1MAPTMAPK1POLBTDP1 | |
| SCHEMBL9984012 | 0.90 | MAPT (0.47) | ALDH1A1SYKRETROS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |