Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.40 |
| ▸ | CDK9 | P50750 | 8/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992440 | 0.89 | IGF1R (0.49) | TBK1CDK9CDC7PIM1IGF1R | |
| SCHEMBL2993667 | 0.79 | TBK1 (0.41) | TBK1CDK9CDC7PIM1CCNT1 | |
| SCHEMBL5541427 | 0.77 | IGF1R (0.41) | CDK9CDC7PIM1IGF1RCCNT1 | |
| SCHEMBL1748948 | 0.76 | IGF1R (0.64) | TBK1CDK9CDC7PIM1IGF1R | |
| SCHEMBL2982565 | 0.76 | IGF1R (0.53) | TBK1CDK9PIM1IGF1RCCNT1 | |
| SCHEMBL2985873 | 0.76 | IGF1R (0.38) | CDK9CDC7PIM1IGF1RCCNT1 | |
| SCHEMBL2989437 | 0.75 | CCNT1 (0.42) | CDK9IGF1RCCNT1CAMKK2 | |
| SCHEMBL2984402 | 0.75 | IGF1R (0.51) | TBK1CDK9CDC7PIM1IGF1R | |
| SCHEMBL2989221 | 0.74 | IGF1R (0.37) | CDK9CDC7PIM1IGF1RCCNT1 | |
| SCHEMBL2985996 | 0.74 | IGF1R (0.48) | TBK1CDK9PIM1IGF1RCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799691-B1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2011-12-21 | — | — | EP | disclosed |