Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987867 | 0.87 | EPHX2 (0.34) | EPHX2 | |
| SCHEMBL1380380 | 0.86 | EPHX2 (0.38) | EPHX2GRM5 | |
| SCHEMBL21827627 | 0.80 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL20535845 | 0.77 | ABL1 (0.38) | EPHX2 | |
| SCHEMBL4207776 | 0.73 | — | — | |
| SCHEMBL4193315 | 0.72 | SMYD3 (0.39) | — | |
| SCHEMBL4196480 | 0.72 | LMNA (0.48) | EPHX2 | |
| SCHEMBL667021 | 0.71 | — | — | |
| SCHEMBL20535521 | 0.71 | CA12 (0.34) | — | |
| SCHEMBL17187735 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397462-A2 | Compounds, compositions and methods of treatment for heart failure | Cytokinetics, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |