Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294042 | 0.92 | NR3C1 (0.56) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL9987879 | 0.80 | NR3C1 (0.34) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL1633458 | 0.78 | NR3C1 (0.72) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL293313 | 0.78 | NR3C1 (0.59) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL5389089 | 0.76 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL1634899 | 0.75 | NR3C1 (0.62) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL292058 | 0.74 | NR3C1 (0.67) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL13823473 | 0.73 | NR3C1 (0.56) | NR3C1NR3C2CYP3A4PGR | |
| SCHEMBL292356 | 0.72 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL5394448 | 0.71 | NR3C1 (0.76) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |