Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.47 |
| ▸ | PGR | P06401 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987974 | 0.85 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL292034 | 0.83 | NR3C1 (0.64) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL9987977 | 0.79 | NR3C1 (0.56) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5809846 | 0.74 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1932794 | 0.74 | NR3C1 (0.59) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291512 | 0.69 | NR3C1 (0.63) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6384154 | 0.68 | NR3C1 (0.69) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL6381395 | 0.67 | NR3C1 (0.68) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5812006 | 0.67 | NR3C1 (0.59) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL5801293 | 0.64 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |