Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984012 | 0.94 | MAPT (0.47) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9983927 | 0.92 | MAPT (0.49) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9987975 | 0.91 | FLT3 (0.46) | TDP1SERPINE1MAPTKMT2AMEN1 | |
| SCHEMBL9983445 | 0.90 | ALDH1A1 (0.45) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9984347 | 0.89 | MAPT (0.43) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9984527 | 0.89 | MAPT (0.43) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9984987 | 0.89 | MAPT (0.42) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9984266 | 0.89 | CDK4 (0.43) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9984594 | 0.89 | CDK4 (0.43) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9984020 | 0.89 | FLT3 (0.46) | MAPTKMT2AMEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |