Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984233 | 0.88 | BRD4 (0.62) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL29695592 | 0.85 | RAB9A (0.59) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL9988186 | 0.83 | MAPT (0.46) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL9985487 | 0.82 | RAB9A (0.46) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL9984430 | 0.81 | HSF1 (0.58) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL9983956 | 0.79 | RAB9A (0.50) | BRD4RAB9ANPC1IDO1GAA | |
| SCHEMBL9985581 | 0.78 | HSF1 (0.60) | BRD4RAB9ANPC1HTTMAPT | |
| SCHEMBL9985056 | 0.78 | HSF1 (0.71) | BRD4MAPTHSF1 | |
| SCHEMBL9985053 | 0.78 | HSF1 (0.71) | BRD4MAPTHSF1 | |
| SCHEMBL9985583 | 0.78 | HSF1 (0.60) | BRD4RAB9ANPC1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |