Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.74 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.74 |
| ▸ | PGR | P06401 | 11/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988214 | 0.90 | NR3C1 (0.91) | NR3C1NR3C2PGR | |
| SCHEMBL9988211 | 0.87 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL292894 | 0.86 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL291605 | 0.82 | NR3C1 (0.76) | NR3C1NR3C2PGR | |
| SCHEMBL291401 | 0.81 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL293471 | 0.76 | NR3C1 (0.79) | NR3C1NR3C2PGR | |
| SCHEMBL3652847 | 0.75 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL15756233 | 0.75 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL5822764 | 0.74 | NR3C1 (0.68) | NR3C1NR3C2PGR | |
| SCHEMBL1931671 | 0.73 | NR3C1 (0.75) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |