SCHEMBL9988331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9988749	0.89	WEE1 (0.59)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15035632	0.89	WEE1 (0.54)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15041336	0.89	CDK4 (0.59)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15036205	0.89	WEE1 (0.52)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15035629	0.87	WEE1 (0.57)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15035634	0.87	WEE1 (0.65)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL15041372	0.87	WEE1 (0.57)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL9988045	0.87	CDK4 (0.70)	CDK4CCND1CCND2CCND3PAK4
	SCHEMBL15035635	0.87	WEE1 (0.56)	WEE1CDK4CCND1CCND2CCND3
	SCHEMBL659714	0.84	CDK4 (0.72)	WEE1CDK4CCND1CCND2CCND3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.