SCHEMBL9988433

SCHEMBL9988433

Cc1ccc(-c2nc3cc4oc(C)nc4cc3o2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.70
KDM4E B2RXH2 10/20 0.70
SMN1; SMN2 Q16637 10/20 0.70
NPC1 O15118 10/20 0.70
RAB9A P51151 10/20 0.70
HPGD P15428 10/20 0.70
HSD17B10 Q99714 5/20 0.70
TP53 P04637 4/20 0.70
MAPT P10636 7/20 0.62
NFKB1 P19838 4/20 0.62
NFKB2 Q00653 4/20 0.62
RELA Q04206 4/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
LMNA P02545 1/20 0.62
POLB P06746 1/20 0.57
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
MMP2 P08253 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13533842 0.98 ALDH1A1 (0.68) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL1643887 0.95 ALDH1A1 (0.68) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL13533846 0.93 ALDH1A1 (0.66) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL23395254 0.93 ALDH1A1 (0.79) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL13035945 0.90 NPC1 (0.63) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL14193959 0.86 SMN1; SMN2 (0.66) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL19601391 0.86 NPC1 (0.76) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL2245237 0.84 SMN1; SMN2 (0.72) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL13533858 0.82 SMN1; SMN2 (0.49) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL13286616 0.82 ALDH1A1 (0.52) ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580380-B2 Polybenzazole fiber and pyridobisimidazole fiber TOYO BOSEKI KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-8297081-B2 Staple fiber yarn, method for producing a textile article, and textile article TEIJIN ARAMID GMBH (DE) 2012-10-30 US disclosed
US-20120159699-A1 PENETRATION-RESISTANT TEXTILE FABRICS AND ARTICLES COMPRISING SAID FABRICS TEIJIN ARAMID GMBH (DE) 2012-06-28 US disclosed
US-7838622-B2 Dope and process for the production of fiber from the dope TEIJIN LIMITED (JP) 2010-11-23 US disclosed
US-7838622-B2 Dope and process for the production of fiber from the dope TEIJIN LIMITED (JP) 2010-11-23 US disclosed
US-20100281923-A1 STAPLE FIBER YARN, METHOD FOR PRODUCING A TEXTILE ARTICLE, AND TEXTILE ARTICLE TEIJIN ARAMID GMBH (DE) 2010-11-11 US disclosed
US-7829482-B2 Thermal performance garments comprising an ultraviolet light tolerant outer shell fabric of polypyridobisimidazole and polybenzobisoxazole fibers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-09 US disclosed
US-7825049-B2 Thermal performance garments comprising a bleach tolerant outer shell fabric of polypyridobisimidazole and polybenzobisoxazole fibers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-02 US disclosed
US-20100233451-A1 POLYBENZAZOLE FIBER AND PYRIDOBISIMIDAZOLE FIBER TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-09-16 US disclosed
US-20100206684-A1 METHOD FOR PRODUCING FIBRIL-EXHIBITING HIGH-PERFORMANCE CHOPPED FIBERS, FIBRIL-EXHIBITING HIGH-PERFORMANCE CHOPPED FIBERS, AND ARTICLES CONTAINING THE SAME TEIJIN ARAMID GMBH (DE) 2010-08-19 US disclosed
US-7465782-B2 Method for making polybenzobisoxazole containing fiber E.I DU PONT DE NEMOURS & COMPANY (US) 2008-12-16 US disclosed
US-7465781-B2 Method for making polybenzobisoxazole containing polymer E.I. DU PONT DE NEMOURS & COMPANY (US) 2008-12-16 US disclosed
US-20080069974-A1 Liquid crystal display panel and fabricating method thereof LG.PHILIPS LCD CO., LTD. 2008-03-20 US disclosed
US-7262266-B2 Copolymerization of polybenzazoles and other aromatic polymers with carbon nanotubes WILLIAM MARSH RICE UNIVERSITY (US) 2007-08-28 US disclosed
US-20070118937-A1 Copolymerization and copolymers of aromatic polymers with carbon nanotubes and products made therefrom WILLIAM MARSH RICE UNIVERSITY (US) 2007-05-24 US disclosed
US-7208109-B2 Changing the solution to nonflowable by absorbing a coagulant, then solvent extraction, for molding a solution of a liquid crystal polymer, polybenzoxazoles or polybenzothiazoles TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-04-24 US disclosed
US-20070015897-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070013102-A1 Method for making polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015899-A1 Polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015898-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed