Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.47 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990151 | 0.94 | RXRA (0.52) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988509 | 0.92 | MALT1 (0.50) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988373 | 0.91 | MALT1 (0.54) | RXRARXRBRXRGMALT1TP53 | |
| SCHEMBL9988479 | 0.91 | MALT1 (0.49) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988840 | 0.91 | MALT1 (0.52) | RXRARXRBRXRGMALT1TP53 | |
| SCHEMBL9988678 | 0.90 | RXRA (0.54) | RXRARXRBRXRGMALT1TP53 | |
| SCHEMBL9989423 | 0.90 | MALT1 (0.48) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988498 | 0.90 | RXRA (0.51) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988866 | 0.89 | MALT1 (0.49) | RXRARXRBRXRGMALT1PANK1 | |
| SCHEMBL9988467 | 0.89 | MALT1 (0.45) | RXRARXRBRXRGMALT1PANK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |