Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83633 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28307197 | 0.85 | — | — | |
| Water SCHEMBL6988845 | 0.85 | — | — | |
| SCHEMBL7175552 | 0.85 | — | — | |
| Water SCHEMBL6988839 | 0.85 | ALDH1A1 (0.47) | — | |
| Hydrogen Sulfide SCHEMBL28249404 | 0.85 | — | — | |
| Iodide SCHEMBL28542335 | 0.85 | — | — | |
| SCHEMBL7718565 | 0.85 | — | — | |
| Thiourea SCHEMBL10336650 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL28299891 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937151-B2 | Carbapenem antibacterials with gram-negative activity | FOB SYNTHESIS, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| EP-2590978-B1 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY | FOB SYNTHESIS INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20150306071-A1 | Carbapenem Antibacterials with Gram-Negative Activity | CHOI, WOO-BAEG, DR. | 2015-10-29 | — | — | US | disclosed |
| US-9149461-B2 | Carbapenem antibacterials with gram-negative activity | FOB SYNTHESIS, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-20130172313-A1 | Carbapenem Antibacterials with Gram-Negative Activity | FOB SYNTHESIS, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2590978-A2 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY | FOB Synthesis, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2011160020-A2 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY | FOB SYNTHESIS (US) | 2011-12-22 | — | — | WO | disclosed |