Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCKAR | P32238 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989687 | 0.94 | MALT1 (0.50) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9990226 | 0.92 | RXRA (0.44) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988729 | 0.92 | MALT1 (0.48) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9990205 | 0.91 | RXRA (0.46) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988942 | 0.91 | TP53 (0.44) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988654 | 0.89 | RXRA (0.44) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988463 | 0.86 | RXRA (0.54) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988460 | 0.86 | MALT1 (0.62) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9989284 | 0.86 | TP53 (0.51) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9989283 | 0.85 | TP53 (0.45) | RXRARXRBRXRGMALT1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |