Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.56 |
| ▸ | C3AR1 | Q16581 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989105 | 1.00 | SUCNR1 (0.56) | SUCNR1C3AR1KDM4EALDH1A1MME | |
| SCHEMBL2247803 | 0.84 | C3AR1 (0.55) | SUCNR1C3AR1 | |
| SCHEMBL13892828 | 0.84 | HPGD (0.72) | ALDH1A1MMEHPGDPOLBHTT | |
| SCHEMBL13892835 | 0.84 | HPGD (0.51) | C3AR1ALDH1A1MMEHPGDPOLB | |
| SCHEMBL26263209 | 0.83 | SUCNR1 (0.61) | SUCNR1C3AR1ALDH1A1HPGDERCC5 | |
| SCHEMBL26264278 | 0.83 | SUCNR1 (0.72) | SUCNR1C3AR1ALDH1A1HPGDERCC5 | |
| SCHEMBL9989814 | 0.81 | FOLH1 (0.54) | SUCNR1C3AR1KDM4EALDH1A1MME | |
| SCHEMBL9989810 | 0.81 | FOLH1 (0.54) | SUCNR1C3AR1KDM4EALDH1A1MME | |
| SCHEMBL4275519 | 0.79 | KMT2A (0.70) | ALDH1A1MMEHPGDSMN1; SMN2LMNA | |
| SCHEMBL4275526 | 0.79 | KMT2A (0.70) | ALDH1A1MMEHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |