Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245141 | 0.87 | C3AR1 (0.61) | C3AR1KMT2ASUCNR1CA2CA1 | |
| SCHEMBL4621088 | 0.86 | C3AR1 (0.46) | C3AR1SUCNR1 | |
| SCHEMBL2247341 | 0.85 | C3AR1 (0.53) | C3AR1KMT2ASUCNR1CA2CA1 | |
| SCHEMBL2247800 | 0.85 | HPGDS (0.52) | C3AR1SUCNR1 | |
| SCHEMBL9989101 | 0.84 | SUCNR1 (0.56) | C3AR1SUCNR1 | |
| SCHEMBL9989105 | 0.84 | SUCNR1 (0.56) | C3AR1SUCNR1 | |
| SCHEMBL2243871 | 0.84 | C3AR1 (0.75) | C3AR1SUCNR1 | |
| SCHEMBL2244829 | 0.83 | S1PR4 (0.48) | C3AR1KMT2ACA2CA1 | |
| SCHEMBL2248654 | 0.82 | TAS1R3 (0.53) | C3AR1KMT2ACA2CA1 | |
| SCHEMBL26264278 | 0.81 | SUCNR1 (0.72) | C3AR1SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998965-B2 | Glutamate aggrecanase inhibitors | WYETH LLC (US) | 2011-08-16 | — | — | US | disclosed |