Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.77 |
| ▸ | PARP2 | Q9UGN5 | 11/20 | 0.77 |
| ▸ | DHODH | Q02127 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970358 | 0.87 | PARP1 (0.72) | PARP1PARP2DHODH | |
| SCHEMBL4974412 | 0.87 | PARP1 (1.00) | PARP1PARP2DHODH | |
| SCHEMBL9989772 | 0.85 | PARP1 (0.65) | PARP1PARP2DHODH | |
| SCHEMBL4968397 | 0.85 | PARP1 (0.75) | PARP1PARP2DHODH | |
| SCHEMBL9988497 | 0.85 | PARP1 (0.66) | PARP1PARP2 | |
| SCHEMBL4971257 | 0.84 | PARP1 (1.00) | PARP1PARP2DHODH | |
| SCHEMBL4971740 | 0.84 | PARP1 (0.74) | PARP1PARP2DHODH | |
| SCHEMBL4988769 | 0.84 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL4969500 | 0.83 | PARP1 (0.73) | PARP1PARP2DHODH | |
| SCHEMBL4973772 | 0.83 | PARP1 (0.79) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038751-A3 | PROCESS FOR THE PURIFICATION OF AROMATIC DICARBOXYLIC ACID | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2012-05-10 | — | — | WO | claimed |
| EP-1957477-B1 | 1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH PHENYL AT THE 2-POSITION ARE POTENT PARP INHIBITORS | ABBOTT LAB (US) | 2011-12-07 | — | — | EP | claimed |