Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.70 |
| ▸ | PARP1 | P09874 | 8/20 | 0.70 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.62 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.62 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | PRKX | P51817 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298432 | 0.85 | DHODH (0.94) | DHODHPARP1 | |
| SCHEMBL505661 | 0.82 | DHODH (1.00) | DHODHPARP1 | |
| SCHEMBL29412034 | 0.82 | PARP1 (1.00) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL458836 | 0.82 | PARP1 (1.00) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL7322715 | 0.82 | PKN1 (0.81) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL505265 | 0.80 | DHODH (0.79) | DHODHPARP1CHEK2 | |
| SCHEMBL505358 | 0.80 | PARP1 (1.00) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL505325 | 0.80 | PKN1 (0.77) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL12673115 | 0.78 | PKN1 (0.57) | DHODHPARP1PKN1PKN2CHEK2 | |
| SCHEMBL12673089 | 0.78 | CYP1A2 (0.57) | DHODHPARP1PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038751-A3 | PROCESS FOR THE PURIFICATION OF AROMATIC DICARBOXYLIC ACID | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2012-05-10 | — | — | WO | disclosed |
| EP-1957477-B1 | 1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH PHENYL AT THE 2-POSITION ARE POTENT PARP INHIBITORS | ABBOTT LAB (US) | 2011-12-07 | — | — | EP | disclosed |