Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | RXRB | P28702 | 2/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 7/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.46 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988871 | 0.93 | RXRA (0.53) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9990250 | 0.92 | RXRA (0.51) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9990231 | 0.91 | RXRA (0.51) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9989595 | 0.90 | RXRA (0.51) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9990146 | 0.89 | RXRA (0.50) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988463 | 0.89 | RXRA (0.54) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9989121 | 0.87 | RXRA (0.52) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988474 | 0.86 | RXRA (0.51) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988516 | 0.86 | RXRA (0.48) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9990073 | 0.86 | RXRA (0.48) | RXRARXRBRXRGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |