Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 13/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 13/20 | 0.61 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.53 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989480 | 1.00 | TAS1R3 (0.61) | TAS1R3TAS1R1C3AR1BCAT1HDAC3 | |
| SCHEMBL12071238 | 0.87 | TAS1R3 (0.65) | TAS1R3TAS1R1BCAT1RAB9APIN1 | |
| SCHEMBL12072230 | 0.87 | TAS1R3 (0.65) | TAS1R3TAS1R1BCAT1RAB9APIN1 | |
| SCHEMBL9989825 | 0.84 | TAS1R3 (0.60) | TAS1R3TAS1R1BCAT1HDAC3HDAC4 | |
| SCHEMBL9989838 | 0.84 | TAS1R3 (0.60) | TAS1R3TAS1R1BCAT1HDAC3HDAC4 | |
| SCHEMBL12071090 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1BCAT1PIN1 | |
| SCHEMBL12072866 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1BCAT1PIN1 | |
| SCHEMBL12071085 | 0.83 | TAS1R3 (0.59) | TAS1R3TAS1R1BCAT1PIN1 | |
| SCHEMBL12072869 | 0.83 | TAS1R3 (0.59) | TAS1R3TAS1R1BCAT1PIN1 | |
| SCHEMBL9989447 | 0.83 | TAS1R3 (0.59) | TAS1R3TAS1R1BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |