Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL28166888 | 0.94 | LMNA (0.53) | LMNAALDH1A1THRBTDP1TSHR | |
| Glycerin SCHEMBL8683268 | 0.94 | LMNA (0.53) | LMNAALDH1A1THRBTDP1TSHR | |
| Glycerin SCHEMBL28192875 | 0.84 | LMNA (0.43) | LMNAALDH1A1THRB | |
| Glycerin SCHEMBL28192874 | 0.84 | LMNA (0.43) | LMNAALDH1A1THRB | |
| Dimethyl Sulfoxide SCHEMBL5090178 | 0.81 | USP2 (0.47) | LMNAALDH1A1THRBTDP1TSHR | |
| Propylene Glycol SCHEMBL6929188 | 0.80 | TDP1 (0.67) | LMNAALDH1A1TDP1TSHRL3MBTL1 | |
| Propylene Glycol SCHEMBL5547967 | 0.80 | — | — | |
| SCHEMBL1847508 | 0.79 | — | — | |
| Glycerin SCHEMBL4251599 | 0.79 | LMNA (0.69) | LMNAALDH1A1THRBTDP1TSHR | |
| Glycerin SCHEMBL3262492 | 0.78 | LMNA (0.82) | LMNAALDH1A1THRBTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480841-B | Crosslinking agent for water-based adhesive and preparation method thereof | 广东灵捷制造化工有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-112480841-A | Crosslinking agent for water-based adhesive and preparation method thereof | 广东灵捷制造化工有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-101874809-A | Local anti-inflammatory external medicinal composition using glycerol DMSO mixed solvent | JIAJUN GONG | 2010-11-03 | — | — | CN | claimed |
| CN-118580393-B | Preparation method of hyaluronic acid solid raw material | 株洲市中建科密添加剂有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-118909807-A | Kluyveromyces marxianus for high-yield of protein and beta-phenethyl alcohol and application thereof | 中国农业科学院饲料研究所 | 2024-11-08 | — | — | CN | disclosed |
| CN-118580393-A | Preparation method of hyaluronic acid solid raw material | 株洲市中建科密添加剂有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-113169516-B | Optical amplifier with larger dynamic range | 华为技术有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3795648-B1 | FORMULATION OF DIMETHYL SULFOXIDE IN MIXTURE WITH AN ADDITIVE CAPABLE OF REDUCING THE CRYSTALLISATION POINT OF THE LATTER, AND USES OF SAID MIXTURE | GAYLORD CHEMICAL COMPANY LLC (US) | 2024-04-03 | — | — | EP | disclosed |
| US-20230381311-A1 | OPTIMIZED RATIOS OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS CONTAINING HIGH CONCENTRATIONS OF PROTEIN-BASED THERAPEUTIC AGENTS | MEDIMMUNE LLC | 2023-11-30 | — | — | US | disclosed |
| CN-116874462-A | Simultaneous response ClO - Viscosity tetraphenyl ethylene-aromatic ring hybridization fluorescent probe and preparation method and application thereof | 新乡医学院第一附属医院 | 2023-10-13 | — | — | CN | disclosed |
| CN-116790490-A | Collagen-combined exosome, exosome freeze-dried powder and preparation method | 中南大学湘雅医院 | 2023-09-22 | — | — | CN | disclosed |
| EP-0137698-A2 | Method of preswelling of regenerated cellulose membranes for organic separations and the use thereof | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4489085-A | Antimicrobial agents and their use employing imidazolyl-enal ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1984-12-18 | — | — | US | disclosed |
| EP-0039814-B1 | IMIDAZOLYL-INDENE-THIOPHENES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |
| EP-0085842-A1 | Antimycosic agents | BAYER AG (DE) | 1983-08-17 | — | — | EP | disclosed |
| US-4349560-A | Antimycotic imidazolyl-indeno-thiophene compounds, composition and method of use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| EP-0041615-A1 | Use of imidazolyl-vinyl ketones and alcohols as antimicrobial agents | BAYER AG (DE) | 1981-12-16 | — | — | EP | disclosed |
| EP-0039814-A2 | Imidazolyl-indene-thiophenes, process for their preparation and their use as medicaments | BAYER AG (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0023614-A1 | Antimycotic compositions containing imidazolylenol ethers, their preparation and their use | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0022969-A1 | Antimycotic compositions containing azolylalkenols and their preparation | BAYER AG (DE) | 1981-01-28 | — | — | EP | disclosed |