Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289614 | 1.00 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL15433960 | 1.00 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL12067203 | 1.00 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL10358548 | 0.90 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL16501556 | 0.90 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL14325977 | 0.90 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL9994530 | 0.87 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| Levomilnacipran SCHEMBL1707471 | 0.87 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| Levomilnacipran SCHEMBL1414867 | 0.87 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL1289654 | 0.87 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011158249-A1 | PROCESS FOR PREPARATION OF MILNACIPRAN INTERMEDIATE AND ITS USE IN PREPARATION OF PURE MILNACIPRAN | GLENMARK GENERICS LIMITED (IN) | 2011-12-22 | — | — | WO | disclosed |