Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997608 | 0.94 | KDM4E (0.55) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL996756 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL997950 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL997612 | 0.82 | TSHR (0.53) | ALDH1A1KDM4EGAATSHRMAPT | |
| SCHEMBL21681999 | 0.82 | POLB (0.53) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL21712206 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL2380055 | 0.79 | KDM4E (0.55) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| SCHEMBL16676773 | 0.78 | ABCB1 (0.66) | ALDH1A1KDM4ESMN1; SMN2GAAPOLB | |
| Hydrochloric Acid SCHEMBL996594 | 0.76 | TSHR (0.47) | KDM4ESMN1; SMN2GAATSHRMAPT | |
| SCHEMBL21709871 | 0.76 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |