Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 17/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 17/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.59 |
| ▸ | SRC | P12931 | 16/20 | 0.51 |
| ▸ | BRAF | P15056 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15021980 | 0.87 | HCK (0.57) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL2933845 | 0.85 | HCK (0.65) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL9994902 | 0.82 | HCK (0.47) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL15022843 | 0.81 | MAPK12 (0.63) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL15034575 | 0.78 | HCK (0.44) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL15040932 | 0.78 | HCK (0.46) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL15021995 | 0.76 | MAPK12 (1.00) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL20386669 | 0.76 | MAPK14 (0.83) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL2931611 | 0.75 | BRAF (0.66) | HCKMAPK14MAPK12SRCBRAF | |
| SCHEMBL3758499 | 0.74 | HCK (0.62) | HCKMAPK14MAPK12SRCBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582700-A2 | RESPIRATORY FORMULATIONS AND COMPOUNDS FOR USE THEREIN | Respivert Limited (GB) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011158044-A2 | RESPIRATORY FORMULATIONS AND COMPOUNDS FOR USE THEREIN | RESPIVERT LIMITED (GB) | 2011-12-22 | — | — | WO | disclosed |