Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996881 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2PFKFB3ALDH1A1HSD17B10PFKFB4 | |
| SCHEMBL29721313 | 0.78 | CYP3A4 (0.52) | SMN1; SMN2ACLYCYP3A4FABP4 | |
| SCHEMBL29721254 | 0.78 | CYP3A4 (0.52) | SMN1; SMN2ACLYCYP3A4FABP4 | |
| SCHEMBL1127184 | 0.78 | CYP3A4 (0.52) | SMN1; SMN2ACLYCYP3A4FABP4 | |
| SCHEMBL787938 | 0.77 | PFKFB3 (0.71) | PFKFB3ACLYALDH1A1HSD17B10PFKFB4 | |
| SCHEMBL9997159 | 0.75 | HSD17B10 (0.62) | PTK2BPFKFB3ACLYALDH1A1HSD17B10 | |
| SCHEMBL28925258 | 0.75 | MCL1 (0.56) | PFKFB3ACLYALDH1A1HSD17B10MCL1 | |
| SCHEMBL28637555 | 0.75 | KMT2A (0.58) | PFKFB3ACLYALDH1A1HSD17B10MCL1 | |
| SCHEMBL2158732 | 0.73 | IKBKB (0.60) | ACLYMEN1KMT2A | |
| SCHEMBL574453 | 0.73 | PTGES2 (0.54) | PTK2BSMN1; SMN2ACLYCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |