SCHEMBL9997371

SCHEMBL9997371

O=S(=O)(O)CCC[Si](O)(O)O.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.46
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
LMNA P02545 1/20 0.38
SLC6A6 P31641 1/20 0.38
CYP2C19 P33261 1/20 0.38
BLM P54132 1/20 0.38
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216512 0.97 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
Silicate SCHEMBL7261577 0.88 APP (0.41) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL7263088 0.81 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL3236569 0.80 PTGS1 (0.43) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL28606908 0.78 APP (0.37) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL28613965 0.78 APP (0.37) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL962806 0.77 APP (0.44) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL424022 0.77 APP (0.44) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL4300905 0.77 APP (0.44) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL30054204 0.77 BBOX1 (0.37) APPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160122640-A1 Silicon Precursors for Sunthesizing Multi-Elemental Inorganic Silicon-Containing Materials and Methods of Synthesizing Same NITTO DENKO CORP (JP) 2016-05-05 US claimed
US-20110315926-A1 SILICON PRECURSORS FOR SYNTHESIZING MULTI-ELEMENTAL INORGANIC SILICON-CONTAINING MATERIALS AND METHODS OF SYNTHESIZING SAME NITTO DENKO CORPORATION (JP) 2011-12-29 US claimed
US-20160122640-A1 Silicon Precursors for Sunthesizing Multi-Elemental Inorganic Silicon-Containing Materials and Methods of Synthesizing Same NITTO DENKO CORP (JP) 2016-05-05 US disclosed
US-20110315926-A1 SILICON PRECURSORS FOR SYNTHESIZING MULTI-ELEMENTAL INORGANIC SILICON-CONTAINING MATERIALS AND METHODS OF SYNTHESIZING SAME NITTO DENKO CORPORATION (JP) 2011-12-29 US disclosed