Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.57 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996982 | 0.90 | ALDH1A1 (0.81) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997320 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9996886 | 0.85 | ALDH1A1 (0.74) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9996954 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL1130086 | 0.82 | MCL1 (0.68) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997030 | 0.81 | PFKFB3 (0.70) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997031 | 0.80 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997334 | 0.80 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997289 | 0.79 | PFKFB3 (0.61) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL9997057 | 0.79 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |