Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286656 | 0.99 | LPAR1 (0.48) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2335059 | 0.92 | LPAR1 (0.41) | LPAR1LPAR2LPAR3LMNAGAA | |
| SCHEMBL2225515 | 0.91 | LPAR1 (0.41) | LPAR1LPAR2LPAR3LMNATSHR | |
| SCHEMBL3714448 | 0.90 | LPAR1 (0.41) | LPAR1LPAR2LPAR3ENPP2MAPT | |
| SCHEMBL3707724 | 0.90 | LPAR1 (0.43) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2341767 | 0.89 | LPAR1 (0.44) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2338529 | 0.89 | LPAR1 (0.44) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2337674 | 0.88 | LPAR1 (0.46) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2335503 | 0.87 | LPAR1 (0.44) | LPAR1LPAR2LPAR3LMNAABCC4 | |
| SCHEMBL2341431 | 0.86 | IP6K1 (0.40) | GAAMAPTTP53ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159550-A2 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND USES THEREOF | AMIDRA PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | WO | claimed |