SCHEMBL9999755

SCHEMBL9999755

C=CCCc1ccc(-c2ccc(-c3ccc(C)cc3)cc2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.38
RARB P10826 3/20 0.38
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
S1PR1 P21453 1/20 0.37
FFAR4 Q5NUL3 3/20 0.37
PTGES2 Q9H7Z7 1/20 0.36
TAAR1 Q96RJ0 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
FFAR1 O14842 2/20 0.36
RARA P10276 1/20 0.35
RARG P13631 1/20 0.35
KIF11 P52732 1/20 0.34
PTGS2 P35354 1/20 0.34
RPS6KA3 P51812 1/20 0.33
DGAT1 O75907 1/20 0.33
SOAT1 P35610 1/20 0.33
CHKA P35790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597904 1.00 BACE1 (0.38) BACE1RARBPDE3BPDE3AS1PR1
SCHEMBL13253176 0.93 RARB (0.39) BACE1RARBPDE3BPDE3AS1PR1
SCHEMBL13253197 0.93 BACE1 (0.42) BACE1RARBPDE3BPDE3AS1PR1
SCHEMBL18540027 0.93 TAAR1 (0.39) RARBTAAR1RARARARGKIF11
SCHEMBL6059171 0.89 BACE1 (0.38) BACE1RARBPDE3BPDE3AS1PR1
SCHEMBL16789601 0.89 RARB (0.43) RARBS1PR1TAAR1RARARARG
SCHEMBL9999856 0.89 RARB (0.40) RARBS1PR1TAAR1RARARARG
SCHEMBL15180193 0.89 RARB (0.43) RARBS1PR1TAAR1RARARARG
SCHEMBL12760546 0.89 RARB (0.40) RARBS1PR1TAAR1RARARARG
SCHEMBL20219122 0.87 TAAR1 (0.42) RARBPDE3BPDE3ATAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230323207-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-8524117-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2013-09-03 US disclosed
US-8524117-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2013-09-03 US disclosed
US-20130207038-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130207038-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130187092-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-07-25 US disclosed
US-8454858-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2013-06-04 US disclosed
US-8236390-B2 Liquid-crystalline medium MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-08-07 US disclosed
US-20120161073-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-06-28 US disclosed
US-20100320420-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-12-23 US disclosed
US-20100176341-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-07-15 US disclosed